循证医学文献检索策略2013.pptVIP

ClinicalTrials (/) 中国临床试验注册中心(/) 提 纲 循证医学与医学文献 原始研究证据检索示例 原始研究证据检索示例1 Insecticide-treated vs non-insecticide-treated bed nets for preventing malaria Children peek out from under an ITN in their home in Uganda. Children under the age of 5 and pregnant women are most vulnerable to malaria infections.  “malaria ” search #1 malaria* #2 plasmodium* #3 “blackwater fever” #4 “marsh fever” #5 Malaria[Mesh] #6 #1 or #2 or #3 or #4 or #5 Marsh Fever Fever, Marsh Paludism Remittent Fever Fever, Remittent Infections, Plasmodium Infection, Plasmodium Plasmodium Infection Plasmodium Infections “bed-net ” search #7 nets* or bednet* or bed-net* or curtain* or “mosquito net” or insecticide-treated or “insecticide treated” #8 Exp“Bedding and Linens”[mh] Mosquito Nets #9 “Mosquito control” [Mesh] #10 #7 or #8 or #9 “ RCT… ” search #11 randomized controlled trial [pt] #12 controlled clinical trial [pt] #13 radomized [tiab] #14 placebo [tiab] #15 drug therapy [sh] #16 radnomly [tiab] #17 trial [tiab] #18 groups [tiab] #19 #11 or #12 or #13 or #14 or #15 or #16 or #17 or #18 #20 animals [mh] not (humans [mh] and animals[mh]) #21 #19 not #20 Search results #6 and #10 and #21 Malaria Bed-net RCT… 例2, 系统性红斑狼疮(SLE)女性患者使用避孕方法的安全性评估 例3:含铂类药物的辅助性化疗用于早期子宫颈癌 谢 谢 ！ 仇 晓 春 上海交通大学医学院 信息资源中心 Tel: 021 Email: tsg2@ * * This is often referred to as the evidence pyramid. It is used to illustrate the evolution of the literature. The base of the pyramid is where information usually starts with an idea or laboratory research. As these ideas turn into drugs and diagnostic tools they are tested in laboratories models, then in animals, and finally in humans. The human testing may begin with volunteers and go through several phases of clinical trials before the drug or diagnostic tool can be authorized for use within the general population.