Evidence Based Pathology H pylori stool.pptVIP

Evidence Based PathologyH. pylori stool antigen test Shubnum Chaudhery Medical College of Georgia 12.7.06 Introduction First described in 1984 Curvilinear, Gram Negative Rod Colonizes gastric mucosa only over 200 genetically diverse strains identified Introduction Epidemiology Most prevalent infection world wide Commonly acquired during childhood 10% by age 10 60% by age 60 Low socioeconomic In U.S., more common in Blacks/Hispanics Transmission Route Fecal-oral Oral-oral Introduction Spectrum of H. pylori disease Asymptomatic infection in most (70%) Establishes a chronic infectious state Pe