关于抗癌中草药有效成分的研究.doc

福建警察学院 学生毕业论文（设计） 关于抗癌中草药有效成分的研究 学生姓名 ： 钟 标 平 学号 ： 1130217962 系部 ： 法 律 系 专业 ： 法 学 指导教师 ： 摘 要：癌症已成为仅次于心血管疾病的人类第二类杀手，目前抗癌常用化疗与放疗的方法可造成对人体不利的严重毒副反应。从化学合成药物寻找抗癌药的难度远远超过从传统中药寻找新药。因此，使用中草药来抗癌，寻找抗癌中草药的有效成分，并对其进行化学、药理及临床研究，成为国内外药物化学工作者的研究重点之一。本文将通过探讨了中草药及其有效成分在抗癌中的研究现状, 为进一步从中草药中发掘高效低毒的抗癌创新药物提供参考。 关键词：抗癌；中草药；有效成分；研究 目 录 1.抗癌中草药·····················································3 1.1莪术························································3 1.2白花蛇舌草··················································3 1.3姜黄························································3 1.4陈皮························································3 1.5丹参························································3 1.6半枝莲······················································3 2.目前发现的具有抗癌症作用的活性成分主要有下列几类···············3-6 2.1生物碱······················································3-4 2.2黄酮类······················································4 2.3萜类（terpenoids）··········································5 2.4脂肪油类····················································5 2.5皂苷类······················································5 2.6多糖························································6 2.7 其他抗癌成分···············································6 3.传统中药存在许多抗癌有效成分···································6-7 4.加强中药抗癌活性成分研究方法···································7 5.结束语·························································7 近年来, 国内外对中草药抗癌有效成分的研究高度重视,利用高通量快速筛选、组合化学及基因工程等新的手段, 加快新药的研究步伐, 随着分子生物学、分子药理学对癌症本质和作用机制方面的阐明, 抗癌中草药有效成分的研究水平有了明显提高。本文将通过对抗癌中草药的有效化学成分的研究进行综述对近些年来的抗癌中草药化学研究前沿文献进行整理、分析与总结。从而加强对中草药抗癌有效成分研究。坚持以中医药理论为基础，与国际接轨。学习使用先进科学手段与标准，确立以疗效为中心的指导思想。化学为药效服务，利用生物工程技术，从传统中草药中筛选抗癌有效成分。 近几十年来, 我国广大医药工作者在中草药及其有效成分的抗癌作用研究方面进行了大量的实验与研究, 取得了丰硕的成果。现将近年来关于抗癌中草药有效成分的研究概况综述如下： 1.抗癌中草药 很多中药研究者，对现有的中药资源进行了体内外抗癌症筛选试验研究，实验结果显示，很多中药具有不同程度的抗癌作用。临床常用抗癌中药有白花蛇舌草、夏枯草、七叶一枝花、凤尾草、半枝莲、天冬、补骨脂、薏苡仁、黄芪、人参、党参、虫草、女贞子、丹参、当归、莪术、姜黄、柴胡、姜黄、陈皮、雷公藤等等。 1.1莪术 中药莪术中主要