动脉粥样硬化与他汀治疗童南伟教授__培训课件.pptxVIP

动脉粥样硬化和他汀治疗四川大学华西医院 童南伟 他汀治疗动脉粥样硬化的获益他汀疗效与剂量他汀治疗现状美国冠心病死亡率显著下降51%49%N Engl J Med 2007;356:2388-98.治疗与危险因素控制对冠心病死亡率降低的贡献PCI for chronic angina (1.3%)治疗领域中PCI = 2.4%/46.6% = 5.2%Statin = 8.5%/46.6% = 18.2%CABG for chronic angina3.7%Statin primary preventionSmoking 11.7%SBP 20.1%T. Chol 24.2%Physical A. 5.1%BMI -7.6%DM -9.8% 4.9%Risk factorReduction 44%危险因素+治疗降胆固醇 = 24.2% 他汀 = 8.5%调脂 = 32.7%Tx of HT7%9%Tx of HF10%2nd prevention post AMI or PCI(including statins) Initial Tx for AMI and UA 11%糖尿病综合管理对预防大血管事件意义重大C-Cholesterol (LDL)（2006）他汀治疗率17%…B-BPA-