消化性溃疡疾病遗传药理学幻灯片.pptVIP

CYP2C19不同基因型对不同剂量PPI抑制胃酸分泌的影响 RMs基因型病人中相同剂量不同给药次数对RPZ抑制胃酸分泌的影响 Cimetidine 、ranitidine与FMO3 Cimetidine 、ranitidine与FMO3 Cimetidine 、ranitidine与FMO3 RM（CYP2C19）病人高剂量PPIs的治愈率 Cure rates of H. pylori infection by treatment with high doses of a PPI plus amoxicillin PP＝per protocol analysis, OPZ＝omeprazole, LPZ＝lansoprazole, RPZ＝rabeprazole PPIs与Clarithromycin药物相互作用 Mean (±SE) plasma levels of omeprazole (OPZ) in the RM, IM, and PM groups with and without clarithromycin (CAM). Mean ± SE plasma concentration–time curves of clarithromycin and AUC values for clarithromycin in the three different gen