冠心病论文冠心病患者血清尿酸水平与中医病理因素痰瘀的相关性研究.docVIP

冠心病论文：冠心病患者血清尿酸水平与中医病理因素痰、瘀的相关性研究 【中文摘要】本研究在收集冠心病病例资料基础上对相关数据进行统计学分析,以期寻找冠心病患者血清尿酸水平与冠心病中医病理因素“痰”、“瘀”的相关性,为冠心病中医辨证提供客观化的依据,从而更好的指导临床辨证及治疗冠心病。探讨血清尿酸(UA)水平与冠心病中医病理因素痰、瘀的相关性,为冠心病中医辨证提供客观化的依据,从而更好的指导临床辨证及治疗冠心病。方法：收集184例冠心病患者的四诊资料,抽血检测血清UA水平,采用2*2析因分析,探讨血清UA水平与冠心病中医病理因素“痰”、“瘀”是否具有相关性,指导临床对于冠心病的辨证论治。结果：1.将病例分为有“痰”、无“痰”组时,UA水平有“痰”组高于无“痰”组,两组间存在统计学差异；将病例分为有“瘀”、无“瘀”组时,UA水平有“瘀”组高于无“瘀”组,两组间亦存在统计学差异；将病例按痰、瘀性质不同分为4组：痰浊组、瘀血组、痰瘀互结组、非痰非瘀组,UA水平痰浊组瘀血组非痰非瘀组痰瘀互结组,且各组间均存在统计学差异。将病例按性别分组后发现,男、女病例组UA水平均提示有“痰”组无“痰”组,且组间均存在统计学差异；女性组中,UA水平在痰浊组与瘀血组、痰浊组与非痰非瘀组、瘀血组与非痰非瘀组、痰瘀互结组与非痰非瘀组存在显著差异。以UA为应变量,痰浊积分为自变量作直线回归时发现UA水平与痰浊积分存在线性相关。2.以UA为应变量,Cr为自变量作直线回归时发现UA水平与Cr水平存在线性相关。正常范围内的Cr水平在有“痰”组无“痰”组；有“瘀”组无“瘀”患者；分4组时发现Cr平均水平瘀血组痰浊组痰瘀互结组非痰非瘀组,但4组间无统计学差异。3.TG水平有“痰”组无“痰”组,有“瘀”组无“瘀”组。HDL值非痰非瘀组痰瘀互结组痰浊组瘀血组,但各组间不存在统计学差异(P0.05)。结论：冠心病患者血清UA水平与中医病理因素痰浊密切相关,且UA水平与痰浊症候积分呈线性正相关。UA水平与血Cr水平存在正线性相关性。血脂水平与冠心病患者中医病理因素间未发现存在统计学上的相关性,有待进一步大样本严格控制的研究验证。 【英文摘要】This paper is basically about clinical data collecting on the basis of coronary heart disease,the data were statistically analyzed to search for the correlation between serum uric acid in coronary heart disease and the medicine pathological factors “sputum,” “stasis “, providing an objective basis for the discrimination of Coronary Heart Disease,so as to better guide the clinical discrimination and treatment of coronary heart disease.:To investigate the correlation between the serum uric acid (UA) levels and pathological factors of coronary heart disease associated traditional Chinese medicine, providing an objective basis for the discrimination of Coronary Heart Disease, so as to better guide the clinical discrimination and treatment of coronary heart disease.Methods:184 cases of the four diagnostic information in patients with coronary heart disease,draw blood for the serum UA levels, using 2*2 factorial analysis the correlation of serum UA level and pathologic factors in Coronary Heart Disease “sputum,” “ stasis “ to guide clinical diagnosis and treatment for coronary