阿司匹林超越抗栓作用.pptVIP

谢谢！ 阿司匹林通过选择性抑制COX-2，抑制花生四稀酸转变为前列腺环素和前列腺素合成的环氧合酶，阻断其致血管扩张、渗透性增强、水肿与合成 PG 和白三稀过程中产生自由基超氧化物阴离子（ O-2 ）和羟基（ OH ），具有防止溶酶体膜破坏和白细胞游走等介导的炎症反应而达抗炎目的。 * Recent studies have suggested that aspirin and stimulation of various mitogen-activated protein kinase aspirin-like compounds have a variety of actions in activities and inhibition of nuclear factor binding kB site addition to their well-studied ability to inhibit cyclooxy- (NF-kB) activation. Moreover, aspirin-like compounds genases. These actions include inhibition of the uncou- have recently been shown to have previously unapprecipling of oxidative p