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角膜塑形镜治疗后光学区偏离中心的角膜地形图参数分析 目的：探讨角膜塑形镜治疗后光学区偏中心距离与角膜地形图参数关系 方法：应用Tomey TMS-4角膜地形图系统对196例患者配戴角膜塑形镜前的角膜地形图进行定量分析，以角膜顶点为参考点，检测治疗后光学区中心与角膜顶点的距离，即为偏中心距离，分析偏中心距离与患者治疗前有关参数之间的关系，分析偏中心距离大小对视功能的影响，统计分析应用spss19.0软件。 结果：治疗1个月平均偏中心距离≤0.5mm者86只眼（25.4%），0.5~1.0mm者161只眼（47.6%），1.0mm~1.5mm者约88只眼（26.0%），≥1.5mm者约3只眼（0.8%）；治疗前不同Kf、Avek及SAI与治疗后镜片偏中心距离比较，差异有统计学意义（单因素方差分析，p＜0.05）；治疗前Ks、Es、Em及SIR值与治疗后镜片偏中心距离比较，差异无统计学意义（单因素方差分析，p＜0.05）；角膜颞侧与鼻侧屈光力差值和治疗后偏中心距离比较，差异有显著统计学意义（Logistic回归分析，p=0.00）。治疗后有无发生重影和眩光者间的治疗后镜片偏中心距离比较，差异均有统计学意义（t检验，均为p=0.00）。 结论：角膜塑形镜治疗后镜片偏离中心的发生与患者的角膜形状密切相关，镜片偏离中心影响治疗后患者的视功能。 Topographical evaluation on decentration of orthokeratology lenses [Abstract] Objective To evaluate the correlative factors of decentration of orthokeratology lenses and its effect on the visual function.Methods Tomey TMS-4 was used for the computer-assisted analysis of corneal differential topographical maps.The examination of corneal topography was proceeded on patient before the fitting of orthokeratology lenses and 1-month later.The distance from center of optic zone to apex of the cornea was measured as the value of decentration of orthokeratology lenses.The factors influenced the value of decentration were analyzed,including the initial corneal curvatures , astigmatism ,eccentricity(E) , surface asymmetry index(SAI) ,surface regularity index(SIR) and horizontal refratciton difference. The data were analyzed using ANOVA test and Logistic test in SPSS 19.0 to discuss the reasons of lens eccentric.Results After one month treatment,the distance of decentration was less than 0.5mm in 25.4% eyes,0.5-1.0mm in 47.6% eyes,1.0-1.5mm in 26.0% eyes and ≥1.5mm in 0.8% eyes.Patients with greater Ks、Avek and SAI showed greater distance of decentration(p＜0.05). There were no atatistically significant difference in the distance of decentration between two groups with different corneal eccentricities , astigmatism and SIR(P＞0.05).The difference was significant which nasal anterior cornea curvatures were larger