2型糖尿病70例临床治疗分析.docVIP

2型糖尿病70例临床治疗分析 　　doi：10.3969/j.issn.1007-614x.2014.16.19 　　摘 要 目的：探讨2型糖尿病的临床治疗方法。方法：2010年2月-2013年4月收治2型糖尿病患者70例，采用数字单双号的模式将其随机分成对照组与治疗组，每组35例。对照组单用二甲双胍缓释片进行治疗，治疗组采用二甲双胍缓释片联合甘精胰岛素进行治疗。结果：治疗后，治疗组23例患者情况为理想，11例患者情况为良好，仅有1例患者无效，总有效率97.14%；对照组中15例患者情况为理想，12例患者情况为良好，8例患者无效，总有效率77.14%。治疗组的总有效率明显高于对照组，差异具有统计学意义（P0.05）。结论：2型糖尿病患者在口服降糖药的基础上，每天睡前注射一次长效胰岛素，能够有效控制空腹血糖，治疗效果较为理想，值得临床推广运用。 　　关键词 2型糖尿病 临床治疗 甘精胰岛素 二甲双胍缓释片 　　Clinical treatment analysis of 70 cases with type 2 diabetes 　　Yu Guang 　　The Health Center of Banqiao Town，Shouxian County，Anhui 232262 　　Abstract Objective：To explore the clinical treatment of type 2 diabetes.Methods：70 cases with type 2 diabetes were selected from February 2010 to April 2013.They were randomly divided into the control group and the treatment group by using digital single and double mode.Each group had 35 cases.The control group were treated with metformin sustained-release tablets.The treatment group were treated with metformin sustained-release tablets combined with insulin glargine.Results：After treatment，in the treatment group， 23 cases were ideal，11 cases were good，only 1 case was ineffective，and the total effective rate was 97.14%.In the control group， 15 cases were ideal，12 cases were good，8 cases were ineffective，and the total effective rate was 77.14%.The total effective rate of the treatment group was apparently higher than that of the control group.The difference was statistically significant（P0.05）.Conclusion：For the patients with type 2 diabetes，on the basis of the oral medications，long-acting insulin is injected before going to bed every day，which can effectively control the fasting glucose.Its treatment effect is ideal，so it is worthy of clinical application. 　　Key words Type 2 diabetes；Clinical treatment；Insulin glargine；Metformin sustained-release tablet 　　2型糖尿病是指因为环境、遗传等多方面的因素共同影响下而引发的以慢性血葡萄糖水平上升为特点的慢性代谢性疾病。长时间的蛋白质、碳水化合物、脂肪代谢紊乱会导致多个系统受到损害，情况严重的会引发高血糖高渗、酮症酸中毒等危及生命的并发症，对患者的生命安全造成巨大的威胁。鉴于此，我院于2010年开始采用二甲双胍缓释片联合甘精胰岛素治疗