干细胞临床应用201203要点.ppt

CytokineReceptor BCAP PDK1 Gab1 PI3K IRS1 Syk IKK Cot NF-κB Pathway CyclinD1 PIP3 PDK1 MDM2 14-3-3 PRAS40 P47phox Grb10 14-3-3 mTOR Protein Synthesis Raptor 4E-BP1 elF4E TSC2 TSC1 GβL Cell Survival F0x01 Cell Cycle P21cip1 GeneticInstability Chk1 Cell Death P53 P73-MediatedApoptosis YAP 14-3-3 BlockApoptosis XIAP Glycogen Synthesis GSK-3 Glycogen Synthase GPCR Gα GTP PI3Kγ PTEN PP2A Akt CTMP Akt Ras PI3K Gab2 PIP3 PIP3 Integrin PI3K ILK FAK Paxillin Jak1 PI3K PIP3 PI3K HSP90 DNA-PK WNK1 Cell Growth Raf1 Erk p70S6K Bad 14-3-3 Bcl-xl eNOS NO JNK Pathway ASK1 Apotosis Androgen Receptor Cel