定量检测pct对细菌性肺炎的诊断价值精编.doc

山西医科大学 定量检测血清降钙素原对细菌性肺炎的诊断价值 摘要：目的 探求血清中降钙素原( PCT )的定量检测对细菌性肺炎的患者的临床诊断价值。方法 选取2013年11月至2014年3月入我院的肺炎患者共82例,其中有病毒性肺炎28例、细菌性肺炎27例、支原体肺炎27例并且和30例健康的体检者做对比，所有患者均在入院第二日清晨空腹抽取静脉血，对照组是空腹12小时后静脉取血。检测血沉（ESR）、白细胞（WBC）、C反应蛋白(CRP)、降钙素原(PCT)的水平。结果 WBC：病毒性肺炎组与细菌性肺炎组具有统计学意义(P0.01),而其他各研究组间无统计学差异(P0.05);CRP：支原体肺炎组与病毒性肺炎组间无统计学差异，而其它各组间均具有统计学意义（P0.05）;PCT：细菌性肺炎组与其它各组间都具有统计学意义(P0.01)，正常对照组与病毒性肺炎组、支原体肺炎组，三个组间无统计学意义；ESR:三组肺炎组与正常对照组间均有统计学意义（P0.05），其余各组间无统计学意义。而以PCT0.5ng/ml为阳性的阈值，对正常对照组、病毒性肺炎组、支原体肺炎组、细菌性肺炎组的PCT阳性率进行比较，可以知道细菌性肺炎组PCT阳性远远高于其它各组，并且病毒性肺炎组、支原体肺炎组和正常对照组无统计学差异。结论 PCT全定量检测是一个能较好的鉴别细菌性肺炎和由其他因素引起的肺炎的指标, 对于肺炎患者的早期诊断与鉴别及对临床抗生素治疗有指导意义。 关键词:肺炎；降钙素原；感染; Quantitative detection of serum procalcitoninin diagnosis ofbacterial pneumonia Abstract Objective To explore the serum procalcitonin (PCT) clinical diagnostic value of quantitative detection of bacterialpneumonia patients. Method From 2013 November to 2014 march in our hospital patients with a total of 82 cases of pneumonia, compared with 28 cases of viral pneumonia, 27 cases of bacterial pneumonia, 27 cases of mycoplasma pneumonia and 30 healthy volunteers were, all patients were taken venous blood on the second day with fasting , the control group was taken venous blood after 12 hours . Erythrocyte sedimentation rate (ESR),white blood cell (WBC), C reactive protein (CRP),procalcitonin (PCT) level. Result WBC: significant viral pneumonia and bacterial pneumoniagroup (P0.01), while the other research group had no significant difference (P0.05); CRP group: Mycoplasma pneumonia and viral pneumonia group had no significant difference, while the other three groups was statistically significant (P 0.05); PCT: bacterial pneumonia group and the other groups were statistically significant (P0.01),normal control group and viral pneumonia group,mycoplasma pneumonia group, no statistical significancebetween the three groups had statistical significance;group ESR: three pneumonia group and the normalcontrol group (P0.05