生物信息学云中的大基因组数据大学毕业论文英文文献翻译及原文.docVIP

毕 业 设 计（论文） 外 文 文 献 翻 译 文献、资料中文题目：生物信息学云中的大基因组数据 文献、资料英文题目：Big Genomic Data in Bioinformatics Cloud 文献、资料来源： 文献、资料发表（出版）日期： 院 （部）： 专 业： 班 级： 姓 名： 学 号： 指导教师： 翻译日期： 2017.02.14 Big Genomic Data in Bioinformatics Cloud Abstract The achievement of Human Genome project has led to the proliferation of genomic sequencing data. This along with the next generation sequencing has helped to reduce the cost of sequencing, which has further increased the demand of analysis of this large genomic data. This data set and its processing has aided medical researches. Thus, we require expertise to deal with biological big data. The concept of cloud computing and big data technologies such as the Apache Hadoop project, are hereby needed to store, handle and analyse this data. Because, these technologies provide distributed and parallelized data processing and are efficient to analyse even petabyte (PB) scale data sets. However, there are some demerits too which may include need of larger time to transfer data and lesser network bandwidth, majorly. 人类基因组计划的实现导致基因组测序数据的增殖。 这与下一代测序一起有助于降低测序的成本，这进一步增加了对这种大基因组数据的分析的需求。 该数据集及其处理有助于医学研究。 因此，我们需要专门知识来处理生物大数据。 因此，需要云计算和大数据技术（例如Apache Hadoop项目）的概念来存储，处理和分析这些数据。 因为，这些技术提供分布式和并行化的数据处理，并且能够有效地分析甚至PB级的数据集。 然而，也有一些缺点，可能包括需要更大的时间来传输数据和更小的网络带宽，主要。 Introduction The introduction of next generation sequencing has given unrivalled levels of sequence data. So, the modern biology is incurring challenges in the field of data management and analysis. A single humans DNA comprises around 3 billion base pairs (bp) representing approximately 100 gigabytes (GB) of data. Bioinformatics is encountering difficulty in storage and analysis of such data. Moores Law infers that computers double in speed and half in size every 18 months. And reports say that the biological data will accumulate at even faster pace [1]. Sequencing a human genome has decreased in cost from $1