Reconstitution of Dryvax Smallpox Vaccine对Dryvax 174重建天花疫苗.pptVIP

Reconstitution of Dryvax? Smallpox Vaccine As taken from the Package Insert, Dec. 2002 Preparation of Vaccine Diluent and instructions for reconstitution will be supplied with vaccine. Vaccine may be used for 60 days following reconstitution. Vaccine must be reconstituted by a pharmacist, pharmacy technician or nurse. Glove Both Hands Prior to Opening Vaccine Vial Prior to Opening Vaccine Vial Record date of reconstitution on the bottle prior to performing the reconstitution. 1. Lift up tab of aluminum seal on vaccine vial. DO NOT BREAK OFF OR TEAR DOWN TAB. 2. Wipe off vial stopper with an alcohol sponge and allow to dry. 3. Place vaccine vial upright on a hard, flat surface. Insert a sterile 21 gauge or smaller needle into the rubber stopper to releasethe vacuum from the vaccine vial. Discard the needle in biohazard waste container.  4. To reduce viscosity of cold diluent, warm by holding diluent-cartridge in palm of hand for a few minutes. 5. Peel open the needle package (provided with the kit) and aseptically remove the needle 6. Remove rubber cover from end of the diluent syringe. 7. With a twisting motion, aseptically attach the vented needle to the hub of the diluent syringe. 8. Remove protective cover from the vented needle and expel the air from the diluent syringe. 9. Aseptically insert the needle through the rubber stopper into the vaccine vial up to the first hub. 10. Depress the plunger to ensure the entire volume of diluent is delivered into the vial. 11. Withdraw diluent syringe/vented needle and discard in biohazard waste container. 12. Allow vaccine vial to stand undisturbed for 3 to 5 minutes. Then if necessary, swirl vial gently to effect complete reconstitution. The vaccine may have a yellow tint and appear more viscous which is within normal limits for the vaccine. 13. Place small piece of cardboard between the vaccine vial and the cold pack. Do not place vaccine vial directly on the cold pack. Storage