·药物与临床·.PDFVIP

·药物与临床· 盗汗宁颗粒治疗盗汗和自汗的临床疗效评价Δ ＊ # 吴文飞 ，李玉平 ，张 青，李 俊，徐 瑛（同济大学附属上海市肺科医院，上海 200433） 中图分类号 R285.6；R969.4 文献标志码 A 文章编号 1001-0408（2015）02-0239-05 DOI 10.6039/j.issn. 1001-0408.2015.02.33 摘 要 目的：评价盗汗宁颗粒治疗气阴不足、肺卫不固者的盗汗、自汗的临床有效性和安全性。方法：将我院结核科收治并符合 诊断和纳入标准的患者132例随机均分为对照组与治疗组。对照组采用常规抗结核或抗感染等对症基础治疗，同时服用模拟盗 汗宁颗粒的阴性对照颗粒；治疗组的基础治疗同对照组，同时服用盗汗宁颗粒。两组患者每次服用1袋颗粒剂，每日2次，连用14 d。治疗前后检查和比较中医证候、体征，肝肾功能和血、尿常规等。用复合的疗效判定标准判断疗效。结果：治疗后，治疗组的各 项疗效指标均显著好于对照组，不良事件的发生率治疗组低于对照组。结论：盗汗宁颗粒治疗气阴不足、肺卫不固者的盗汗、自汗 有效性和安全性良好。 关键词 盗汗宁颗粒；盗汗；自汗；气阴不足；肺卫不固 Evaluation of Clinical Efficacy of Daohanning Granules in the Treatment of Night Sweating and Spontaneous Sweating WU Wen-fei ，LI Yu-ping ，ZHANG Qing ，LI Jun ，XU Ying （Shanghai Pulmonary Hospital Affiliated to Tongji Uni- versity ，Shanghai 200433，China ） ABSTRACT OBJECTIVE ：To evaluate the clinical efficacy and safety of Daohanning granules in the treatment of night sweating and spontaneous sweating with either deficiency of qi-yin or insecurity of lung-defense. METHODS ：132patients admitted to tuber- culosis department of our hospital conforming to diagnosis and inclusion criteria were randomly assigned into control group and treatment group. Both groups were given conventional antitubercular or anti-infection and other relative symptomatic treatment. Con- trol group was additionally given Daohanning granules negative control and treatment group additionally received Daohanning gran- ules. They were all given one bag of granules each time ，twice a day for consecutive 14d. TCM syndromes ，physical signs ，liver and kidney functions ，blood and urine tests ，etc. were determined and compared before and after treatment. The clinical efficacies of 2 groups were judged by complex efficacy evaluation criteria. RESULTS ：After treatment ，various clinical efficacy index of treatment group were significantly better than those