《微小RNA及其在医学中的应用》培训课件.pptVIP

These results indicated that overexpression of miR-10b is sufficient to promote both migration and invasion in vitro. 5.1 miR-10b? cell migration and invasion in vitro 5.2 miR-10b ? tumour invasion in vivo 5.3 miR-10b ? distant metastasis in vivo 5.4 how miR-10b expression is regulated? 5. 5 What is a direct and functional target of miR-10b? 5.6 miR-10b expression is elevated in metastatic breast tumours 5.2 miR-10b ? tumour invasion in vivo implanted miR-10b-transduced or mock-infected SUM149 cells into the mammary fat pads of NOD-SCID mice(该品系鼠为非肥胖糖尿病/严重联合免疫缺陷鼠，不但成熟T、B细胞联合免疫缺陷