Dr.MollySmith.pptVIP

Pulmonary Ventilation during Exercise Ventilation in Steady Rate Exercise During light moderate steady rate exercise, VE:VO2 linear relationship. Ventilatory equivalent for oxygen (VE:VO2): ratio of minute ventilation to oxygen uptake. Usually 25 : 1 during submaximal exercise up to 55% max. Ventilation in Steady Rate Exercise Ventilatory response to fixed level of submaximal exercise can be divided into 4 phases. Sudden increase at onset. Ventilation gradually increases to higher steady-rate level. Steady state level of ventilation maintained. Recovery period gradual return to resting levels. Phase IV higher than resting levels coincide with EPOC. Ventilation in Steady Rate Exercise Ventilatory equivalent for carbon dioxide (VE:VO2): ratio of minute ventilation to carbon dioxide produced. Remains constant during steady rate exercise because pulmonary ventilation eliminates CO2 . Ventilation in Non-Steady-Rate Exercise Minute ventilation (VE) increases in proportion to oxygen consumption over range from rest to moderate exercise. VE increases dispropor-tionately to oxygen consumption over range from moderate to strenuous. Ventilation in Non-Steady-Rate Exercise The point at which ventilation increases disproportionately with oxygen uptake during incremental exercise is termed: ventilatory threshold (VT). Ventilation in Non-Steady-Rate Exercise Lactic acid generated during anaerobic glycolysis is buffered in blood by sodium bicarbonate. Lactic acid + NaHCO3 → Na Lactate + H2CO3 → H20 + CO2 Ventilation in Non-Steady-Rate Exercise The excess, non-metabolic CO2 stimulates ventilation. Recall that metabolic CO2 is produced in Krebs Cycle in oxidation of acetyl CoA. Ventilation in Non-Steady-Rate Exercise The non-metabolic CO2 from buffering HLa drives increased VE to eliminate it, so VE: VCO2 remains constant. The increased in VE exceeds increase in VO2 disproportionately. The point at which VEO2 breaks with linearity is the ventilatory threshold. Ventil