雌激素联合甲硝唑治疗萎缩性阴道炎的临床疗效观察.docVIP

雌激素联合甲硝唑治疗萎缩性阴道炎的临床疗效观察 　　摘要：目的 观察雌激素联合甲硝唑治疗萎缩性阴道炎的临床疗效。方法 选取2014年12月～2015年12月我科室接诊的106例萎缩性阴道炎患者临床资料，将其随机分为对照组和观察组，每组53例患者。对照组患者采用甲硝唑治疗，观察组患者在对照组治疗的基础上采用雌激素治疗，对比两组患者临床治疗疗效。结果 观察组患者临床治疗有效率明显高于对照组，差异有统计学意义（P0.05）；观察组患者表层细胞百分比明显高于对照组，差异有统计学意义（P0.05）；观察组患者阴道pH、白带清洁度明显优于对照组，差异有统计学意义（P0.05）。结论 雌激素联合甲硝唑治疗萎缩性阴道炎疗效确切，效果明显优于单纯使用甲硝唑治疗效果，并且可以明显改善患者表层细胞百分比，促进阴道白带清洁度的恢复，值得在临床推广和应用。 　　关键词：雌激素；甲硝唑；萎缩性阴道炎 　　Abstract：Objective To observe the clinical effects of estrogen joint metronidazole atrophic vaginitis. Methods Choose between December 2014 and December 2014 during my department accepts the clinical data of 106 patients with atrophic vaginitis， were randomly divided into control group and observation group，53 cases in each group. The control group were treated by a file after treatment， the observation group of patients in the control group， treatment with estrogen therapy on the basis of comparing the clinical curative effect of two groups of patients. Results The clinical treatment of patients with efficient observation group was obviously higher than that of control group， the difference was statistically significant（P0.05）； Surface cells in patients with percentage of observation group was obviously higher than that of control group， the difference was statistically significant（P0.05）； Observation group of patients with vaginal pH， leucorrhea cleanliness was better than control group， the difference was statistically significant （P0.05）.Conclusion Combined therapy with metronidazole estrogen atrophic vaginitis curative effect， the effect is better than simply using metronidazole treatment effect， and can significantly improve patients with percentage of surface cells， promote the recovery of vaginal cleanness of leucorrhea， is worth in clinical promotion and application. 　　Key words：Estrogen； Metronidazole；Atrophic vaginitis 　　随着人们生活环境和生活方式的不断转变，女性妇科疾病发病不断增加。萎缩性阴道炎是临床一种妇科炎症性疾病，通常绝经期患者较为常见。卵巢是雌激素分泌的主要器官，随着年龄的不断增加，卵巢功能逐渐衰退，导致女性体内雌激素水平降低，特别是绝经期容易发生一系列的病理变化。例如阴道粘膜萎缩、变薄、