白血病-chu解析.pptVIP

* * * * * * * * * * * * * * * * * * * * the drug should work in all period of cell cycle the dosage should be full the regimen would be used repeatedly why full ? Killing the cells in all period of cell cycle repeatedly could make G0→ cycle control the source of relapse use Combination regimen of these drugs which have different action, typing and toxicity to increase curative effect and decrease toxicity why combine ? end cell apoptosis Go (source of relapse) sensitive