用于乳腺普查的电阻抗扫描系统的硬件设计.pdfVIP

第 29 卷第 6 期 2∞8 年 6 月 仪器仪表学报 Chinese Joumal of Scientific Instrument VoL 29 No.6 Jun. 2ω8 用于乳腺普查的电阻抗扫描系统的硬件设计* 李振宇，史学涛，克，富生，付峰，刘锐岗，萤秀珍 (第四军医大学生物医学工程系 西安 71∞32) 摘 要:为实现可用于i临床乳腺普沓的电阻扰成像硬件系统，从临床普查角度出发分析硬件系统的设计要求，进行基于平板电 极阵列方式的回抗扫描成像破件系统设计。建立了一个多频电阳抗扫描硬件系统，经定标电阻网络对系统的性能进行了评估， 激励源输出幅值为1. 0V 时，幅度倍噪比为 80 拙，相位噪声 O. ∞15 0 ;相应采集倍号幅度倍噪比为ω 拙，相位噪声 0.05 0 0 系统 可以识别 1% 的阻抗变化。物理模型实验表明，系统可识别 2mmx2mmx2mm 的高电导率目标体。硬件系统精度高，模型实 验证明本系统满足临床乳腺检测的需要，~且要在临床实验中进一步验证。 关键词:电阻抗成像;乳腺癌;硬件设计 中图分类号:阳18 文献标iR码 :A 国家标准学科分提代码: 310.6110 Hardware desi阴 of el时triωlimpe归nce 配剧时吨 system for breast sc附时ng Ji Zhenyu , Shi Xuetao , You Fusheng , Fu Feng , Liu Ruigang , Dong Xiuzhen (Medical Electronic Engineering Departmem , Fourth Military Medical University , Xian 710032 , China) Abstract: Objective:ωimplement an electrical impedance imaging system for clinical breast screening. Me也od: from the aspect of clinical screening , the design requirements of the hardware system are analyzed. An electrical im幽 pedance scanDing (EIS) hardware system using plane electrode 町ay w剧 desi伊ed. Result: a multi-frequency EIS hardware system was setup and was assessed using calibration resistance network. For 1. OV output of the stimulating source , the amplitude-SNR is about 80 dB and the phase-noise is about O. ∞50. Correspondingly , the amplitude- SNR of the measured signal is 60 dB , and its phase幽noise is about O. 05 0 ? ln one-frame measured data , 1 % imped- ance difference could be detected by the system. A 2 mm x 2 mm x 2 mm-target with a higher conductivity could be detected in a physical phantom experiment. Conclusion: the hardware system features high performance , physical phantom experiment demonstrates that the system meets the requirement of clinical breast detection; but it stíll needs to he validated in clinical experiment. Key words: electrical impedance imaging; breast cancer; ha,rdware design 1 引 乳腺瘤是妇女常见的一种恶性肿瘤，严囊威胁妇女的 健康，早期诊断和治疗是一种有效的方法[1] 。目前常用的 乳脚癌珍断设备(X-ray 、U1trasound 、MRl等)主要有以下不 足 :1 )