RNA interference as a gene knockdown technique.pdfVIP

RR G D a A A K R S T M E C o d s 1 dThe International Journal of Biochemistry Cell Biology 42 (2010) 1243–1251 Contents lists available at ScienceDirect The International Journal of Biochemistry Cell Biology journa l homepage: www.e lsev ier .com/ locate /b ioce l eview NA interference as a gene knockdown technique e Shan ? epartment of Molecular, Cellular, and Developmental Biology, Yale University, P. O. Box 208103, New Haven, CT 06520, United States r t i c l e i n f o rticle history: vailable online 12 May 2009 eywords: NA interference (RNAi) ystematic herapeutics orpholino GS a b s t r