简介序列比对的工具.ppt

Sequence analysis 資料格式 (Data format) 資料格式 （Text） MTEITAAMVKELRESTGAGMMDCKNALSETNGDFDKAVQLLREKGLGKAAKKADRLAAEGLVSVKVSDDFTIAAMRPSYLSYEDLDMTFVENEYKALVAELEKENEERRRLKDPNKPEHKQFASRKQLSDAILKEAEEKIKEELKAQGKPEKIWDNIIPGKMNSFIADNSQLDSKLTLMGQFYVMDDKKTVEQVIAEKEKEFGGKIKIVEFICFEVGEGLEKKTEDFAAEVAAQLTVSEINSETDFVAKNDQFIALTKDTTAHIQSNSLQSVEELHSSTINGVKFEEYLKSQIATIGENLVVRFATLKAGANGVVNGYIHTNGRVGVVIAAACDSAEVASKSRDLLRQICMH 資料格式 （FASTA） SEQUENCE_1 MTEITAAMVKELRESTGAGMMDCKNALSETNGDFDKAVQLLREKGLGKAAKKADRLAAEG LVSVKVSDDFTIAAMRPSYLSYEDLDMTFVENEYKALVAELEKENEERRRLKDPNKPEHK IPQFASRKQLSDAILKEAEEKIKEELKAQGKPEKIWDNIIPGKMNSFIADNSQLDSKLTL MGQFYVMDDKKTVEQVIAEKEKEFGGKIKIVEFICFEVGEGLEKKTEDFAAEVAAQL SEQUENCE_2 SATVSEINSETDFVAKNDQFIALTKDTTAHIQSNSLQSVEELHSSTINGVKFEEYLKSQI ATIGENLVVRRFATLKAGANGVVNGYIHTNGRVGVVIAAACDSAEVASKSRDLLRQICMH 資料格式 （GenBank） 資料格式 （Swissport） 資料庫比對搜尋 Database Search 其他資料庫(Others) Signaling pathway, metabolic pathway…… 資料庫種類 文獻資料庫(Reference database) PubMed, Books, OMIN, SeqAnalRef 序列資料庫(Sequence Database) Nucleotide, protein /entrez/query.fcgi?db=PubMed Reference database /entrez/query.fcgi?db=Books Reference database /entrez/query.fcgi?db=OMIM Reference database /seqanalref/ Reference database .tw/ Reference database Sequence Databases Nucleotide database -DNA -mRNA/cDNA -Alternative spicing -SNP -UniGene Protein Database - Sequences - Domain and family - Structure - Swiss-2D %3D Image - ENZYME - PDB International DNA data banks / Data Bank http://www.ebi.ac.uk/Databases/ Data Bank http://www.ddbj.nig.ac.jp/ Data Bank /mapview/ Genome Brower /cgi-bin/hgGateway Genome Brower / Genome Brower Expression Sequence Tag http://cdna.ims.u-tokyo.ac.jp/ mRNA/cDNA Database /dbEST/index.html mRNA/cDNA Database /UniGene/ mRNA/cDNA Database Alternative splicing /ASAP2/ Alternative Splicing Annotation Project II :8080/ BIPASS Single Nucleotide Polymorphism (SNP) /SNP/ SNP database .tw/snp/ SNP database /sprot/ Protein database /prosite/ 這是一個以蛋白質功能為分類基準的資料庫， 資料庫內的 資料包括了蛋白質的生化功能 、