高等有机化学-Lecture11综述.pptVIP

The Pinacol Rearrangement semi-pinacol rearrangement Tiffeneau-Demjanov Group moved as the following order: tertiary alkyl＞aryl＞H＞secondary alkyl ＞primary alkyl＞methyl The cumene hydroperoxide rearrangement is quite resemble the Baeyer-Villiger Rearrangement Important industrial reaction for manufacturing phenol and acetone Memory effects Longer Nucleophilic Rearrangement Free-Radical Rearrangements Electophilic Rearrangements 例 Favorskii Rearrangement Mechanism of Favorskii Rearrangement For asymmetric cycloprapanone, the stable anion form dominantly Different α- chloroketone form