PAPILLOMAVIRUSES.pptVIP

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  • 2017-04-20 发布于湖北
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PAPILLOMAVIRUSES

PAPILLOMA VIRUSES;Papilloma Viruses;;Papilloma Viruses;HPV 16;Infectious Cycle;HPV 16, 31 Genome Structure;HPV 16, 31 Genome Structure;Functions of HPV Proteins;Viral Replication Surges in Keratinocytes; p53 normally induces apoptosis of cells that should not be dividing such as Keratinocytes p53 neutralization is achieved by ubiquitination which leads to proteasome degradation similar to Rb, p53 mutations are observed in a variety of cancers; p53 normally is in low levels in the cytosol and inactive In stress conditions: increase in phosphorylation occurs making it more stable Increase in

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