Biofunctionalized magnetic-vortex microdiscs for targeted cancer-cell destruction.pdfVIP

ARTICLES PUBLISHED ONLINE: 29 NOVEMBER 2009 | DOI: 10.1038/NMAT2591 Biofunctionalized magnetic-vortex microdiscs for targeted cancer-cell destruction Dong-Hyun Kim1, Elena A. Rozhkova2*, Ilya V. Ulasov3, Samuel D. Bader1,2, Tijana Rajh2, Maciej S. Lesniak3 and Valentyn Novosad1* Nanomagnetic materials offer exciting avenues for probing cell mechanics and activating mechanosensitive ion channels, as well as for advancing cancer therapies. Most experimental works so far have used superparamagnetic materials. This report describes a first approach based on interfacing cells with lithographically