TitleIdentificationofionicchloroacetanilide-herbicide.docVIP

Title:?Identification of ionic chloroacetanilide-herbicide metabolites in surface water and groundwater by HPLC/MS using negative ion spray Author(s):? HYPERLINK /CIW.cgi?SID=W2hjF1fLOBcF5edbC9FFunc=OneClickSearchfield=AUval=Ferrer+Icurr_doc=395/1Form=FullRecordPagedoc=395/1 \o one-click search Ferrer I,  HYPERLINK /CIW.cgi?SID=W2hjF1fLOBcF5edbC9FFunc=OneClickSearchfield=AUval=Thurman+EMcurr_doc=395/1Form=FullRecordPagedoc=395/1 \o one-click search Thurman EM,  HYPERLINK /CIW.cgi?SID=W2hjF1fLOBcF5edbC9FFunc=OneClickSearchfield=AUval=Barcelo+Dcurr_doc=395/1Form=FullRecordPagedoc=395/1 \o one-click search Barcelo D Source:?ANALYTICAL CHEMISTRY 69 (22): 4547-4553 NOV 15 1997 Document Type:?Article Language:?English  HYPERLINK /CIW.cgi?SID=W2hjF1fLOBcF5edbC9FFunc=PagedCitedRefListUT=A1997Yoc=395/1rec_id=102796149 Cited References: 13?????  HYPERLINK /CIW.cgi?SID=W2hjF1fLOBcF5edbC9FFunc=DispCitingRecdoc=395/1isickref=102796149 Times Cited: 57????? ? Abstract:?Solid-phase extraction (SPE) was combined with highperformance liquid chromatography/high-flow pneumatically assisted electrospray mass spectrometry (HPLC/ESP/MS) for the trace analysis of oxanilic and sulfonic acids of acetochlor, alachlor, and metolachlor. The isolation procedure separated the chloroacetanilide metabolites from the parent herbicides during the elution from C-18 cartridges using ethyl acetate for parent compounds, followed by methanol for the anionic metabolites. The metabolites were separated chromatographically using reversed-phase HPLC and analyzed by negative-ion MS using electrospray ionization in selected ion mode, Quantitation limits were 0.01 mu g/L for both the oxanilic and sulfonic acids based on a 100-mL water sample, This combination of methods represents an important advance in environmental analysis of chloroacetanilide-herbicide metabolites in surface water and groundwater for two reasons. First, anionic chloroacetanilide metabolites are a major class o