病例选择和标本保存对流感病毒分离率的影响.pdfVIP

中国热带医学 年第 卷第 期 · 338 · CHINA TROPICAL MEDICINE Vol.12 No.3 March 2012 2012 12 3 ·短篇论著· 病例选择和标本保存对流感病毒分离率的影响 胡青坡，宋海红 摘要：目的 研究流感病毒分离率的影响因素。 方法 收集周浦医院 2008 年采集的流感样病例咽拭子标本的 相关资料，进行 logistic 回归分析。 结果 2008 年周浦医院流感样病例病毒分离率为 53.27%。经 logistic 回归分析， 发病季节和接种时间是流感病毒分离率的影响因素，咳嗽或咽痛、送样时间（48 小时之内）对流感病毒分离率影响在 统计学上无意义。 结论 样品收集 48 小时内进行检测；一季度和三季度是流感病毒活跃期，尽量多采集样本。有无 咳嗽或咽痛在统计学上无意义。加强流感病例发病特点及我国 ILI 评估的研究。 关键词：流感；病毒分离率；影响因素；logistic 回归分析 中图分类号：R373.1+3 文献标识码：B 文章编号：1009- 9727（2012）3- 338- 03 Effect of case selection and preservation of specimen on the isolation of influenza virus. HU Qing- po，SONG Hai- hong.（Pudong New Area，Shanghai Municipal Centre for Disease Control and Prevention，Shanghai 201300，P. R. China） Abstract：Objective To investigate the facors influencing the isolation of influenza virus. Methods The data and throat swab speciimens of influenza- like cases in Zhoupu Hospital in 2008 were collected and analyzed with Logistic regression analysis. Results The isolation rate of influenza- like illness is 53.27% in Zhoupu Hospital of Shanghai in 2008. By Logistic regression analysis，cough or throat pain and sample delivery（in 48h）were not the influencing factors on the isolation rate of influenza virus. Conclusion The samples be assayed within 48 hours after collection for improving the positive rate of influenza virus isolation. With and without cough or throat pain are not factors statistically associated with th