1044312118医学资料-甲基强的松龙在脊柱非创伤性疾病治疗中的应用-北京大学第三医院骨科-孙宇.pptVIP

甲基强的松龙在脊柱非创伤性疾病治疗中的应用Methylprednisolone Usein Orthopedic Conditions(Non-traumatic Spinal Diseases);MP的药理作用 Pharmacologic Effect of MP in SCI (Hall 1981-85);MP的药理作用 Pharmacologic Effect of MP in SCI (Hall 1981-85);1、减轻脊髓和神经根细胞膜水肿 2、抑制神经细胞膜和轴突、树突的脂质过氧化进程 3、抑制一般性炎症反应和作用 Relieving edema of cell membranes of spinal cord and nerve roots Inhibiting lipid peroxidation of nerve cell membrane, axons and dendrites Suppressing general inflammatory reaction;4、间接改善局部血液循环 5、抑制细胞的凋亡 6、减轻再灌注损伤 4. Indirectly improving local blood circulation 5. Inhibiting apoptosis 6. Relieving reperfusion injury ;常见