临床常见病原菌的耐药分析.pdfVIP

齐齐哈尔医学院学报 2008 年第 29 卷第 2 期 ? 131 ? 临床常见病原菌的耐药分析 詹燕婷 E 摘要】 目的 了解近两年多来临床分离的常见病原菌对临床常用抗生素的耐药情况.为临床合 理用药提供依据.方法 用梅里埃公司生产的 GP_GN 鉴定卡 AST 药敏分析卡对近两年多临床所 有分离菌进行鉴定和药敏分析，统计临床常见病原菌对临床常用抗生素的耐药牟.结果 革兰氏阳性 球菌对青霉素的耐药率很高，并呈逐年上升趋势，而加.抑制剂的青霉素类合剂相对不如酶抑制剂的青 酶素其耐药牟明显减低，万古霉素对其耐率最低，但已出现了耐万古霉素肠 III 菌.革兰氏阴性菌对许多 抗生素的耐药率也呈上升趋势，亚舷培南对其活性最高.结论 本院近年常见病原茵的耐药鉴别分析 结果显示临床分离的耐药性已相当严重，并呈上升趋势，应引起临床上的重视. E 关键词 E 常见病原菌 h[ 药分析 Antimicrobial susceptibility ofωmmon pathogen ZHAN Yan - ting. (Department of Clinical Labora? tory. Longyuan People s Hospital. Longyuan, Fujian 364000 China) (Abstract) Objective To study the resistance of clinical commonly seen isolated pathogen from 2005 to 2007 in order to o[fer the physicians the basis of using antibiotics reasonably. 如leth叫s Bio? merieux Companys GN 、 GP 、 AST-vitek cards were used to identify the bacteria and detect antimicrobial and calculated the resistant rates to the antibiotics commonly used. Re雷目 15 The rats of penicillin - re? sistant Gram - positive bacteria were higher and higher. but penicillin with the emzyme- inhibitant sensi? tive to them . Vancomycin was still very sensitive to them. But Vanconycin - relistant entercocci had ap? peared. The negative bacteria resistance also increased year after year ? but Imipenem was very effective. ωnclusions The resistance of microbe has come to be more and more serious. We must pay more att凹 tlOn to It. (Key words) Common Pathogen Resistance analysis 随着临床抗生素的广泛使用，细菌耐药性逐渐 按微生物检验常规进行。 产生，细菌对药物的敏感性不断发生变化，往往引起 1. 1. 2 试刑 法国微生物梅里埃公司生产的 GP 、 临床经验用药的失败。为此，我们对本院 2005 年~ GN 、 AST 等鉴定和药敏卡。 2007 年 10 月