1279 cases of pulmonary tuberculosis drug susceptibility test results re-analysis of.docVIP

 PAGE \* MERGEFORMAT 11 1279 cases of pulmonary tuberculosis drug susceptibility test results re-analysis of Authors: Feng Sujuan ZHAO Li-Xue Xu Xue-wen 【Abstract】 Objective: Drug-resistant Mycobacterium tuberculosis clinical treatment has been a major problem as well as re-treatment of refractory one of the main TB. Reported in the literature are significant differences between high and low resistance rates around, we have summed up the 1996 to 2005, 10-year period 1279 cases of drug-resistant tuberculosis patients re-treated hospitalized experimental results, to understand the rate of drug resistance in Wuhan, in order to provide reference for clinical treatment. Results: 1279 cases of drug resistance in 678 cases of drug resistance rate was 53.0%. Of which 172 cases of resistance to one drug, accounting for 25.4% of the number of drug-resistant cases; 169 cases of resistance to two drugs, accounting for 24.94%; followed by 124 cases for the three drugs, accounting for 18.3%; four drugs in 74 cases, accounting for 11.0%; 5 drugs 58 cases, accounting for 8.6%; 6 drug 42 cases, accounting for 6.2%; 7 drugs 40 cases, accounting for 5.9%. Reported in the literature SM, INH, RFP three kinds of drug resistance rates higher than other drugs, and has been among the top three. This phenomenon is due to H, S, R 3 kinds of drugs in chemotherapy is difficult to replace with other drugs caused. Conclusion: The treatment of multi-drug resistant cases are quite difficult, its efficacy difference is one of the reasons causing refractory tuberculosis. Keywords: drug-resistant tuberculosis, resistance rates Retreatment of tuberculosis, drug resistant strains refractory to their great relationship. Reported in the literature re-treatment of people with low resistance rates accounted for 41.4%, accounting for 94.0% of high, significant differences between high and low. In some areas of the initial drug-resistant TB has also reached 92.4%. We have summar