180 cases of nimodipine on the clinical observation of migraine_0.doc

 PAGE \* MERGEFORMAT 5 180 cases of nimodipine on the clinical observation of migraine [Abstract] Objective To investigate the treatment of migraine nimodipine effects, adverse reactions. Methods 180 patients with migraine were treated with nimodipine 30mg, 3 times a day, orally, for two weeks as a course of multiple courses of treatment available. The results of 180 migraine patients, control 85.0%, effective in 30.0%, 8.3% is not valid. Conclusion Nimodipine for the dihydropyridine calcium channel blockers, by observing, for the treatment of migraine, effect, side effects and safe. [Keywords:] nimodipine, migraine For the calcium channel blocker nimodipine, non-dihydropyridine derivatives, the fat-soluble, easy through the blood-brain barrier, cerebral vascular nerve cells, glial cells, the L of the voltage sensitive Ca2 + channels have selective blockade of a strong role. both in the clinical application to improve the cerebral circulation, have the dual role of protecting neurons. migraine clinical common disease, the incidence of severely affected patients will learn, work, resulting in life quality. In recent years, we tried a total of nimodipine in the treatment of 180 cases of migraine, a significant effect, are as follows. 1 Materials and Methods 1.1 General information on 180 patients from 2003 to 2007 cases in our hospital, meet the 1990 International Conference developed countries of migraine diagnostic criteria for migraine [1]. The degree and frequency of attacks has the disease characteristics. 86 cases were male and , female 94 cases, aged 18 to 50 years, mean 36 years, duration of 3 months to 10 years, an average of 3 years, seizure frequency: 88 patients with 1 episode per month, 2 attacks per month, 47 cases of seizures per month 3 times or more in 45 cases. 1.2 The auxiliary examination All patients in the treatment of eyes before and after investigation, are shown before treatment with varying degrees of changes in retin