1HMRS high-grade gliomas and solitary brain metastasis in differential diagnosis.docVIP

 PAGE \* MERGEFORMAT 15 1HMRS high-grade gliomas and solitary brain metastasis in differential diagnosis Of: Lu Yongming Zhou Jianchun Dingqing Guo Zhen-Jue Chen Wu Jia Chuanhai [Abstract] Objective To study the proton magnetic resonance spectroscopy (1HMRS) in high-grade gliomas, the differential diagnosis of solitary brain metastasis in the application. Methods of collecting pathologically confirmed 18 cases of high-grade gliomas and solitary brain metastases in 12 cases, respectively, with routine preoperative MRI, scan and 1HMRS enhanced inspection, measurement of two tumor parenchyma, central necrosis, peritumoral edema metabolite concentrations (including NAA, Cho, Cr) and ratio changes, and compared and analyzed. results of the two tumors showed so much T1WI, low signal, T2WI showed heterogeneous high signal, with varying degrees of enhancement and peritumoral edema. high-grade gliomas and solitary brain metastasis The 1HMRS tumor parenchyma showed an NAA / Cho, NAA / Cr decrease, Cho / Cr increased, but the difference was not significant; the central necrotic area NAA / Cho, NAA / Cr was significantly, but Cho / Cr was no significant difference; peritumoral edema NAA / Cho, Cho / Cr was significantly, but the NAA / Cr was no significant difference. Conclusion 1HMRS can be non-invasive analysis of brain tumor metabolism and help high-grade gliomas and solitary brain metastasis diagnosis and differential diagnosis. [Keywords:] glioma; metastases; magnetic resonance spectroscopy; magnetic resonance imaging [Abstract] Objective To investigate the value of 1HMRS in differential diagnosis on high-grade gliomas and solitary metastases. Methods 18 patients with high-grade gliomas and 12 patients with solitary metastases were confirmed by pathology. All cases were performed routine MRI, contrast enhanced MRI and 1HMRS preoperatively. Three regions, the solid component, necrosis and peritumoral edema of the two types of tumor, were measured, then the