20 cases of children on the clinical treatment of osteosarcoma.docVIP

 PAGE \* MERGEFORMAT 7 20 cases of children on the clinical treatment of osteosarcoma [Abstract] Objective To investigate the clinical treatment of osteosarcoma in children. Methods 20 children with osteosarcoma, surgery and chemotherapy. Results 12 cases were followed up for 3-year survival rate of children 76%. Conclusions Treatment of osteosarcoma in children in commonly used surgical procedure However, in the treatment of chemotherapy should be run through the entire process. [Keywords:] osteosarcoma, children, chemotherapy, surgery Osteosarcoma (osteosarcoma) is in addition to plasma cells outside of the most common malignant tumor, the difference in the incidence of larger national statistics, about 0.1/10 million to 1 / 10 million. Because the disease occurs in young people during the long bones, from no typical clinical symptoms when the disease is easy to be confused with the trauma, and high malignancy, early metastasis that may occur, the danger great, high mortality rate [1]. We are from January 1996 to December 2007 were treated 20 osteosarcoma in children, are as follows. 1 Clinical data The group of 20 patients, 12 males and 8 females, aged 4 to 13 years, mean 9 years old. Tumor was located in the femur in 8 cases, tibia in 6 cases, humerus in 4 cases, lumbar in 2 cases. The patients were due to patients complained of pain treatment. occurs in joints of patients with varying degrees of limited joint movement and swelling, and some patients misdiagnosed as tuberculosis due to ineffective treatment and treatment by the anti-TB. 2 treatment The use of chemical treatments and surgical treatment, mainly chemotherapy drug for the periodic non-specific drugs [adriamycin (ADM, 30 mg/m2), cisplatin (DDP, 100 mg/m2), cyclophosphamide (CTX, 200 mg/m2 )] and periodic specific drugs methotrexate (MTX, 8 ~ 12 g/m2. this group of children are used to develop a series of Rosen (T4, T5, T7, T10 and T12) in the T7 chemotherapy treatment, tha