52 cases of congenital syphilis diagnosis and treatment of children with.docVIP

 PAGE \* MERGEFORMAT 10 52 cases of congenital syphilis diagnosis and treatment of children with Keywords: in children with congenital syphilis The incidence of syphilis in recent years, a clear upward trend, with women of childbearing age increased the incidence of syphilis, congenital syphilis rate increased significantly. Our hospital since June 2003 to June 2008 were treated 52 cases of early congenital syphilis in children, are analytical report is as follows. A clinical data 1.1 General information on 52 cases of children in the male 31, female 21 cases; admission age lt;1d 21 Li, ~ 7d 17 Li, ~ 14d 10 Li, ~ 28d 4 cases, 19 cases of premature infants (gestational age 30 ~ 36 weeks, including five cases of cesarean section because of fetal distress line), full-term infants 33 (including 10 cases of full-term small for gestational age); mild asphyxia at birth, 8 cases of severe asphyxia in 5 cases. 1.2 in children with clinical manifestations are skin rash, mainly dark red Ban rash and pimples, while 10 cases with small pustules, with 15 cases of skin exfoliation; with perioral, perianal chapped 18 cases; nasal discharge from 8 cases; liver splenomegaly in 26 cases, jaundice in 28 cases, 19 cases of malnutrition, there are varying degrees of anemia in 18 cases, the merger of 16 cases of neonatal aspiration pneumonia, bronchial pneumonia and heart failure, dual-hydrocele, left pulmonary artery stenosis, patent foramen ovale and patent ductus arteriosus in 1 case, neonatal enteritis, multiple organ failure of all 3 cases. 1.3 syphilis serology laboratory tests: 52 cases of children with rapid plasma reagin test (RPR) were positive (1:16 ~ 1:128), Treponema pallidum latex agglutination test (TPPA) were positive; routine blood test: patients children have varying degrees of white blood cells increased (18 ~ 35) × 109 / L, 8 Li thrombocytopenia (26.0 ~ 95.6) × 109 / L, 18 Li Hb decreased (4.5 ~ 11.0g / L); urine rout