About Naoluoxintong on focal cerebral ischemia reperfusion rat neuroepithelial stem cell protein nestin expression.docVIP
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About Naoluoxintong on focal cerebral ischemia reperfusion rat neuroepithelial stem cell protein nestin expression
Of: Chen Agricultural, Wang Jian, Tang Wei, TRADITIONAL
[Abstract] Objective To observe the governing law on behalf of Yiqihuoxue Naoluoxintong traditional Chinese medicine and its decomposition (Qi Fang, Recipe) on focal cerebral ischemia reperfusion model rat subventricular zone (SVZ) neural stem cell proliferation . Methods used suture method of middle cerebral artery rat model of focal cerebral ischemia were observed Yiqihuoxue, Qi, promoting blood circulation 3 prescription therapies and their representatives, after 2 h of ischemia, respectively, reperfusion 1,3,7 d of treatment, SABC immunohistochemistry assay neuroepithelial stem cell protein nestin expression. Results nestin expression in all treatment groups increased, but only 7 d after ischemia compared with the model group There were significant differences (P lt;0.05), Qi and activating blood was significantly increased 7 d after ischemia with the Qi and activating blood method group was statistically significant difference (P lt;0.05). Conclusion After Naoluoxintong (Qi and activating blood circulation) and its decomposition (Qi Fang, blood side) after the intervention, can endogenous neural stem cell proliferation significantly increased Naoluoxintong in promoting the proliferation of neural stem cells (7 d ) is superior to the effects of expression of the split side (Qi Fang, blood side).
[Keywords:] Naoluoxintong, focal cerebral ischemia and reperfusion; neural stem cells, the proliferation of nestin
Keywords:: Naoluoxintong, local cerebral ischemia-reperfusion, neural stem cells, Nestin proliferation
In this experiment, model of focal cerebral ischemia in rats, observed Naoluoxintong its decomposition on cerebral ischemia-reperfusion nestin expression, and to explore Naoluoxintong on focal cerebral ischemia reperfusion model of rat neural s
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