Acalypha cough expectorant Experimental Study.docVIP

 PAGE \* MERGEFORMAT 6 Acalypha cough expectorant Experimental Study Author: Hong-Liang Li Ding Ye Qing Sun Libo Zeng Jing [Abstract] Objective To observe the animal experiments Acalypha of the water extract in mice cough expectorant effect. Methods of sulfur dioxide induced cough in mice, mice were observed ammonia induced cough cough Acalypha role; by phenol red excretion method to observe the role of Acalypha expectorant. The results of drugs of high, medium and low individual doses can significantly reduce sulfur dioxide and ammonia in mice caused by cough frequency, cough significantly extend the incubation period, Acalypha high-dose group are most pronounced. Conclusion Acalypha marked expectorant cough role. [Keywords:] Acalypha cough expectorants Acalypha australis, also known as mejillon with beads Euphorbiaceae Acalypha austrlis L. Acalypha of the whole plant. With the heat, dampness, reduces swelling, detoxification, hemostasis efficacy, civil commonly used in the treatment of enteritis. In vitro was found Acalypha the water extract of a variety of bacteria killing effect, and diarrhea caused by senna with the antagonistic effect [1]. Recent studies have also found that the water extract has expectorant, cough role, in this experiment for its research for the development of the medicinal value of Acalypha provide a scientific basis. 1 Materials and equipment 1.1 herbs Acalypha 500 g were purchased in Ganzhou 39 pharmacies. After crushing the tablets had 40 mesh sieve. Take powder add water infiltration 3 h, and then adding water to 12 times, respectively, 10 times the boiling two times, 1st 2h, 2nd 1.5 h, leaching combined filtrate. Concentrated to 100 ml is equivalent to the original herbs 5 g * ml-1, namely, Acalypha water extract. Codeine phosphate, Kyrgyzstan could Pharmaceutical Co., Ltd. production, batch number 20,051,003; aminophylline, Beijing Pharmaceutical production, batch number 20,060,801; concentrated ammonia, Jiangxi Hongdu che