Acinetobacter baumannii clinical distribution and drug resistance change.docVIP

 PAGE \* MERGEFORMAT 11 Acinetobacter baumannii clinical distribution and drug resistance change Authors: Li Xiang Xin Zhou Tie-li * Zhu Liqing, Wang Chao Fong Sai Yu Fang Zhou Liping [Abstract] Objective To understand the distribution of Acinetobacter baumannii, and the changes of drug resistance, in order to guide clinical use of drugs, provide the basis for infection control. Methods A retrospective survey in January 2002 ~ December 2006 clinical isolates of Acinetobacter baumannii clinical distribution; agar diffusion method and VITEK-AMS detection of Acinetobacter baumannii to ciprofloxacin, ceftazidime, ceftriaxone, Ami card stars and imipenem resistance, imipenem agar dilution minimum inhibitory concentration (MIC). The results of five years, separated from 865 Acinetobacter baumannii mainly from respiratory tract specimens, accounting for 75.7% (655/865), and mainly concentrated in the neurosurgical intensive care unit and other departments; VITEK-AMS and agar dilution Bowman did not susceptibility of Acinetobacter to imipenem significantly different results; Acinetobacter baumannii clinical resistance to antibiotics commonly used in increased year by year, imipenem-sensitive strains of MIC value is also on the rise. Conclusion VITEK-AMS for the detection of Acinetobacter baumannii resistant to imipenem susceptibility exists false; In recent years, Acinetobacter baumannii infection and drug resistance increased significantly, and there continues to rise. [Keywords:] Acinetobacter baumannii; infection; imipenem; resistance; changes Acinetobacter baumannii infections in hospitals, one of the important pathogens in recent years, increasing its resistance, in particular, including the emergence of carbapenem antibiotics, including all were resistant Acinetobacter, to clinical the treatment makes it difficult [1,2]. We are in 2002 ~ 2006 clinical isolates of Acinetobacter baumannii resistance to changes in the distribution and analysis of the circumstanc