Acacia dealbata antipyretic effect of cold particles experimental study.docVIP

 PAGE \* MERGEFORMAT 4 Acacia dealbata antipyretic effect of cold particles experimental study [Abstract] Objective: To study the silver Jing antipyretic effect of cold particles. Methods: 54 SD rats were randomly divided into model group, is Bupleurum particle group, paracetamol group and silver Jing cold particles is small, medium and large-dose group, 9 rats in each group. After the last administration, rats were injected subcutaneously back 2,4  2-nitro-phenol, measuring changes in body temperature in rats; rats rear foot plantar subcutaneous injection of carrageenin foot Liang Zhao Lai rubber suspension, measured changes in rectal temperature . Results: (1) Silver Jing cold particles is small, medium and large-dose group 2,4  2-nitro-phenol-induced fever antipyretic effect of duration of more than 120,150,180 min, respectively; (2) Silver Jing cold particles is small, medium and large-dose group on carrageenin-induced fever Lay plastic duration of antipyretic effect respectively, 4,5,6 h. Conclusion: The Silver Jing cold particles have a better antipyretic effect. [Keywords:] Jing cold silver particles 2 4  2-nitro-phenol plastic fork les Antipyretic Yin Jing cold particles from the honeysuckle, forsythia, Nepeta, Banlangen, wind, and mint etc., is combined with clinical experience of Yinqiaosan made of the Conference, attending Fengreganmao fever, sore throat, whole body aches, cough embolism. We have experiments showed that their influenza B virus and influenza virus have a good inhibitory effect, and has good anti-bacterial, anti-inflammatory and analgesic effects and safety of major. This study was designed to explore its 2,4  2-nitro-phenol and Chondrus Lay plastic-induced fever antipyretic effect. 1 Materials and methods 1.1 Materials 1.1.1 Drugs and reagents silver Jing cold particles: Jiangsu Provincial Hospital of Chinese preparations Department, batch number 040,603; paracetamol: Jiangsu Wing Tai Pharmaceutical Co., Ltd., batch numb