Acute organophosphorus pesticide poisoning diagnosis and treatment of intermediate syndrome.docVIP

 PAGE \* MERGEFORMAT 7 Acute organophosphorus pesticide poisoning diagnosis and treatment of intermediate syndrome [Keywords:] organophosphate poisoning, intermediate syndrome, Diagnosis and treatment of acute organophosphorus pesticide poisoning intermediate syndrome (IMS) is the treatment of acute organophosphorus pesticide poisoning process, after remission of acute symptoms, delayed encephalopathy before the onset of acute poisoning in about 24 ~ 96 h after the sudden death occurs [1]. IMS has unpredictable, unavoidable and unexpected features, and high mortality. I admitted to hospital in the past 9 years of organophosphorus pesticide poisoning were a total of 18 cases IMS, Diagnosis and Treatment of the report now as follows. 1 Clinical data 1.1 General Information January 1999 ~ December 2007 in our hospital with acute organophosphorus pesticide poisoning were 18 cases in IMS, 5 males and 13 females, aged 23 to 58 years, average 35.7 years old, all patients were oral administration of organophosphorus pesticides, 3 cases of oral administration of dimethoate, dichlorvos in 5 cases, 10 cases of pesticide methamidophos. taking the amount of 100 ~ 250 ml, hospitalization time was poisoned 20 min ~ 1 h. After the treatment when the performance of typical poisoning, check choline esterase activity was in severe decline, based on clinical performance and the determination of cholinesterase grading [1], all of severe poisoning, the reception after the verdict, gastric lavage, atropine, pralidoxime (P fixed or chlorine ) injection and other drugs, appears IMS time of ingestion 18 ~ 105 h. 1.2 The early clinical manifestations of all patients had a cholinergic crisis, such as skin clammy, miosis, mouth and nose secretions occur, muscle trembling, disturbance of consciousness and a typical expression of the lung. After treatment to reduce symptoms after sudden chest tightness, speech weakness difficulty swallowing, the rise of weakness, proximal limb