An fluorine implantation of human treatment of advanced lung cancer with pleural effusion 36 cases of.docVIP

 PAGE \* MERGEFORMAT 7 An fluorine implantation of human treatment of advanced lung cancer with pleural effusion 36 cases of Author: Lee Boon Yang, Yang Jun, Chen, Yang Friendship [Keywords:] Lung neoplasms 0 Introduction Nanyang, Henan Medical College Hospital thoracic surgery were treated in patients with advanced lung cancer with malignant pleural effusion 75 cases, of which 36 cases of human use of a certain dose of fluoride for an implantable intrathoracic perfusion chemotherapy, compared with the same period in the control group, regardless of In the short-term effect or toxicity, and other aspects significant clinical effects. An object and method 1.1 Object 75 cases of malignant pleural effusion patients, aged 26 to 81 (mean 59.5) years. Of these 64 cases of clear pathological diagnosis, adenocarcinoma 21 cases, 30 cases of squamous cell carcinoma, small cell undifferentiated carcinoma in 9 cases, adenosquamous carcinoma in 4 cases. 36 cases An acceptance of the chest in patients with implanted human fluoride has a clear pathological diagnosis of 28 cases, adenocarcinoma 11 cases, 15 cases of squamous cell carcinoma, adenosquamous carcinoma in 1 case, small cell undifferentiated carcinoma in 1 case, including 2 patients had liver metastasis, 1 patient with brain metastasis. the remaining 39 patients, the use of other anticancer drugs (such as cisplatin, cyclophosphamide, etc.) pleural infusion. 1.2 Methods All patients treated under local anesthesia with thoracic puncture routinely collected most of the pleural effusion, the human fluoride Security Group by 400 mg/m2 fluorouracil injection of sustained-release implant (human fluorine An), the first 14 days after repeated administration; other drugs groups according to routine clinical application of dose into the chest, 1 ~ 2 times / wk. fluorouracil sustained-release implant of Human Technology Co., Ltd. produced by the Anhui. According to WHO standard requirements were evaluated. CR: complet