Anti-angiogenesis drugs fundus Progress.docVIP

 PAGE \* MERGEFORMAT 28 Anti-angiogenesis drugs fundus Progress [Abstract] retinal and choroidal neovascularization can lead to vitreous hemorrhage, retinal hemorrhage, traction retinal detachment, visual acuity and harm patients. Such lesions commonly found in age-related macular degeneration (age related macular degeneration, AMD), diabetic retinopathy (diabetic retinopathy, DR), retinal vein occlusion (retinal vein occlusions, RVO), retinopathy of premature children (retinopathy of prematurity, ROP) and other ocular fundus. At present, drugs to treat neovascular (neovscularization, NV NV generated mainly for the different inhibited the growth stage. This article reviews the clinical and is currently undergoing clinical trials for the treatment of retinal angiogenesis drugs. [Keywords:] angiogenesis, anti-angiogenesis drugs, retina, choroid Abstract ?r Retina and choroid neovascularization (NV) may induce vitreous hemorrhage, subretinal hemorrhage and tractional retinal detachment and usually result in poor vision. It is often seen in the eyes with age related macular degeneration (AMD), diabetic retinopathy (DR), retinal vein occlusions (RVO) and retinopathy of prematurity (ROP). At present, drugs of NV mainly target the different phases of the angiogenesis and suppress its growth. We discusse the present anti neovascular drugs which are used on clinic or under the clinicaltrial. ?r KEYWORDS: neovascularization; anti neovascular drugs; retina; choroid 0 Introduction Pathological retinal and choroidal blood vessel growth can lead to a series of clinical and pathological changes, such as: vitreous hemorrhage, retinal hemorrhage, traction retinal detachment, a serious threat to those suffering from visual acuity changes. Such lesions commonly found in AMD, DR, RVO, ROP and other ocular fundus. At present ophthalmic neovascular (NV methods are: (1 surgical treatment: such as vitreous surgery, (2 laser treatment: such as laser photocoag