Anti-I-hypersensitivity drink Shufeng Experimental Analysis.docVIP

 PAGE \* MERGEFORMAT 8 Anti-I-hypersensitivity drink Shufeng Experimental Analysis [Abstract]: Objective To study the anti-I-type hypersensitivity Shufeng drinking in rats. Methods I-hypersensitivity caused by egg albumin in animal models, using ELISA method Shufeng drink on Serum Interleukin -4 ( IL-4), interferon-γ (IFN-γ) and immunoglobulin E (IgE) content. Shufeng drinking can increase the model results of IFN-γ serum levels (P lt;0.05), reduced rats Serum IL-4, IgE levels (P lt;0.01). Shufeng chlorpheniramine group drinking group and no significant difference (Pgt; 0.05), Shufeng IFN-γ/IL-4 drinking group than the model group, there were significant differences (P lt;0.05), and chlorpheniramine group and no significant difference (Pgt; 0.05). Conclusion Shufeng drinking prevention of skin type I hypersensitivity diseases (acute urticaria) through the mechanism of action may be related to some cytokine regulation of Th1/Th2 balance of the body affect the. [Keywords:] I-type hypersensitivity Shufeng drink IL -4 interferon-γ immunoglobulin E in rats Abstract: Objective To investigate the effects and mechanism of Shufeng Decoction resisting type I hypersensitivity. Methods Type I hypersensitivity was induced by OVA. The content of IL-4, IFN-γ and IgE in serum of the rats treated by Shufeng Decoction were determined by ELISA. Results Shufeng Decoction can increase the content of IFN-γ in model rats (P lt;0.05), and decrease the content of IL-4 and IgE (P lt;0.01), there was no significant difference between Shufeng Decoction group and chlorpheniramine group (Pgt; 0.05). IFN-γ/IL-4 of Shufeng Decoction was significant higher than model group (P lt;0.05), and there was no significant difference compared with chlorpheniramine group (Pgt; 0.05). Conclusion The effects and mechanism of Shufeng Decoction on prophylaxis and treatment of type I hypersensitivity of skin (acute urticaria) may be related with regulating cell factors and influencing the balance of