Aripiprazole and haloperidol in the treatment of mental disorders caused by brain injury control study.docVIP

 PAGE \* MERGEFORMAT 7 Aripiprazole and haloperidol in the treatment of mental disorders caused by brain injury control study Of: Lujian Rui Xu Xiaogang Zhu Xiujuan Gold Orchid [Abstract] Objective: To compare the aripiprazole and haloperidol in the treatment of brain injury due to the efficacy and safety of mental disorders. Methods: A retrospective analysis of 80 cases of mental disorder caused by traumatic brain injury clinical data set is divided into A prazosin group of 40 patients, haloperidol group of 40 cases (1 case off to the Clinical Global Impression Scale (CGI evaluate the efficacy, adverse drug reactions with the scale (TESS assessment of adverse reactions. Results: There were more treatment CGI score significantly decreased (P lt;0.01, but no significant difference between the two groups. aripiprazole group cure rate of 80.0%, efficiency 97.5%, haloperidol group cure rate of 79.5%, 97.4% efficiency, the two groups the difference was not statistically significant. by TESS rating scale, aripiprazole group, insomnia, nausea and vomiting was significantly more than haloperidol, haloperidol group muscle rigidity, tremor, akathisia, blurred vision, drowsiness , constipation, dizziness, aripiprazole group than the obvious, the total adverse events between the two groups aripiprazole group than haloperidol group (P lt;0.01. Conclusion: Aripiprazole treatment efficacy of mental disorders due to brain injury and haloperidol in the similar overall incidence of adverse events than haloperidol. [Keywords:] brain injury, mental disorder, aripiprazole, haloperidol Aripiprazole and haloperidol in the treatment of brain injury were mental disorders due to better drugs and very effective, but side effects of aripiprazole small and light, good security. In this paper, both efficacy and adverse reactions control study, reported below. 1 Subjects and methods 1.1 study January 2006 to December 2008 hospitalized patients with mental disorders due t