Azithromycin for Injection Anaphylactic shock in 1 case of nursing.docVIP

 PAGE \* MERGEFORMAT 4 Azithromycin for Injection Anaphylactic shock in 1 case of nursing [Keywords:] azithromycin; allergic shock; Care Azithromycin for injection is a second generation semi-synthetic macrolide derivatives, the mechanism is through with the bacterial 50S ribosomal subunit and inhibit protein synthesis dependent on RNA, which in turn has antibacterial activity [1], Gram positive bacteria, some Gram-negative bacteria effectively. because with the absorption, bioavailability, long half-life, tolerance and good, but widely used in clinic. its adverse reactions are gastrointestinal reactions, local reactions, skin reactions , digestive system (dyspepsia, flatulence), nervous system (headache, lethargy), allergic reactions (bronchospasm), the rare occurrence of anaphylactic shock. I Division in the November 30, 2009 rescue allergic shock caused by injection of azithromycin 1 case, and now the rescue process and Nursing reported as follows. 1 Clinical data Patients, male, 67 years old, fever and cough 8 days, on November 29, 2009 admitted to our department of pulmonary infection in hospital. No history of drug allergy. Doctor’s orders to 0.5g of azithromycin for injection and 5% intravenous glucose injection 500ml infusion, day 1, day 2 at about input 300ml, patients with nausea, vomiting, dizziness, shortness of breath, pale, cold sweat, body, lips cyanosis, P 78 times / min, BP 80/50mmHg, immediately withdrawal. prescribed subcutaneous injection of 0.1% epinephrine 0.5ml, oxygen inhalation, intravenous injection of dexamethasone 10mg, 5% glucose infusion 250ml plus 20mg dopamine, such as dual-channel fluid and catheter rescue, about 15min later, the patient sanity turned clear. BP 130/80mmHg, P 75 times / min, go to the ruddy complexion, the condition improved, continue to observe 4h, no adverse reactions, vital signs were stable, a stable condition. 2 Nursing 2.1 General care in patients with allergic reactions should be immediat