Bionic bone titanium implant bone defects in rabbits with Fixed Network.docVIP

 PAGE \* MERGEFORMAT 8 Bionic bone titanium implant bone defects in rabbits with Fixed Network Author: Zhang open, Yan Hongwei, Liu Kai, Liu Tao [Keywords:] bionic bone; titanium network management; bone defect; repair; rabbits Abstract: Objective MHAbBMP bionic bone as an alternative to bone contact of titanium on a limited network management under a fixed model of rabbit femoral defect repair. Methods 48 New Zealand white rabbits were randomly divided into experimental group: MHAbBMP bionic bone + Titanium network management; control group: autologous iliac bone graft + Ti-network management. Be cut in the middle of femoral shaft 10mm, rabbit femoral defect model, MHAbBMP bionic bone / implantation of autogenous iliac bone defect combined with limited-contact titanium Network fixed to repair bone defects. In general rabbits, testing of blood alkaline phosphatase, X-ray, pathology, electron microscopy observation. The results of titanium Network histocompatibility good, fixed stable and effective, both groups of bone defect repaired. Two groups of blood alkaline phosphatase, X-ray findings, histopathological and electron microscope examination of data by the statistical analysis no significant difference. Conclusion limited contact-type titanium implants and network management of bone defect on the stump to play the role of a reliable fixed; MHAbBMP bionic bone and autogenous iliac bone grafting compared with osteoinduction activity quite. Keywords:: biomimetic bone; titanium network management; bone defect; repair; rabbits Bionic bone implantation combined with limited contracted titanium net duct on the repairment of rabbit bone defect ABSTRACT: Objective To investigate the effect of MHAbBMP implantation combined with limited contacted titanium net duct fixation on femoral shaft bone defect in rabbits. Methods A total of 48 rabbits were divided into experimental group (treated with bionic bone MHAbBMP plus titanium net duct) and control group (treated