Bladder cancer and the relationship between sex hormone receptors in Progress.docVIP

 PAGE \* MERGEFORMAT 13 Bladder cancer and the relationship between sex hormone receptors in Progress [Abstract] sex hormones may have bladder cancer and its progress to a certain extent, but the research in this area is still relatively small. Available information shows that estrogen inhibition of bladder cancer have a certain, and male The role of hormones contrast, the specific molecular mechanism is not clear. of the hormone receptor from the structure, distribution and relationship with other aspects of bladder cancer, a brief review, in hopes of bladder cancer diagnosis and treatment of help. [Keywords:] bladder cancer, estrogen receptor, androgen receptor [Abstract] The occurrence and infiltration of bladder carcinoma would be affected by the sexual hormones, however, the data in this area is not too much.Information available suggests that effects of estrogen on bladder cancer are inhibition, while the opposite role of androgen. A specific molecular mechanism remains unclear.In this review, we summarized the relationship between structure, distribution of sexual hormone receptors and bladder cancer to provide some aid to clinical diagnosis and treatment of bladder cancer. [Keywords:] bladder carcinoma; estrogen receptor; androgen receptor; review Bladder cancer is the most common malignant tumor of the urinary system, the United States statistics show that: the incidence of bladder cancer accounts for about systemic tumor incidence of 7%, ranked No. 4, the mortality rate of about 3%, ranked No. 8. Bladder cancer the existence of gender on the incidence of significant differences In 2009 the United States to the latest figures: new cases of bladder cancer in men, 52 810 cases, 170 cases of women and 18 men killed 10,180 cases, 4 deaths in 150 cases of women [1] . In the United States and Europe, male age-adjusted bladder cancer incidence is 2 to 4 times the female [2]. The incidence of bladder cancer are very different between men and