Childhood asthma and allergy and serum total IgE level correlation.docVIP

 PAGE \* MERGEFORMAT 8 Childhood asthma and allergy and serum total IgE level correlation Of: Li Lixin, Zhuang Lingling, Wang Chunlian [Abstract] Objective To evaluate children’s asthma and allergy, the relationship between serum total IgE levels. Methods 120 asthmatic children test group and control group for the same period without respiratory diseases, allergic diseases and family history of children, namely, 48 cases; using sensitive screening method for allergy testing, child Tong Zhimin objects were observed and serum total IgE positive rate level. Results The positive rate was 88.33% allergen, inhalation of dust mite allergens in household dust mite positive the highest rate of ingestion of the allergens in milk, the highest positive rate; control group, the positive rate was 12.5% #8203;#8203;allergen, allergen-positive rate of the two groups of children, the difference was statistically significant (P lt;0.01); experimental serum total IgE increase of 112 cases (93.33%), serum total IgE were elevated in 6 cases (12.5%), total serum IgE levels of two groups, the difference was statistically significant (P lt;0.01). Conclusion of a variety of children with asthma allergens positive reaction to inhaled allergens, which dominated early to avoid contact with allergens, prevention and treatment of childhood asthma has significant; serum total IgE levels in the diagnosis of bronchial asthma facilitating role to play. [Keywords:] Asthma / etiology; allergens; Immunoglobulins; children Bronchial asthma is a common pediatric diseases, the rise in recent years the disease. It is estimated that there are around 150 million children with asthma, the morbidity and mortality rate of 20% every 10 years, the rate increased to 50% [1], serious harm child health. Asthma is caused by various cells (such as eosinophils, mast cells, T lymphocytes, neutrophils and airway epithelial cells) and cellular components participate in chronic inflammatory airway disease,