Chinese herbal medicine active ingredients of tumor cell apoptosis induced by Research.docVIP

 PAGE \* MERGEFORMAT 27 Chinese herbal medicine active ingredients of tumor cell apoptosis induced by Research Before the introduction of the concept of apoptosis, anti-cancer drugs kill tumor cells, the mechanism has been considered by affecting the cell cycle at different time, which eventually lead to necrosis of tumor cells. In fact, the death of tumor cells through apoptosis and necrosis in two ways. Apoptosis and tumor occurrence and development are closely related. More and more studies confirm that many Chinese herbal medicines can induce tumor cell apoptosis. This paper from the formation of the concept of apoptosis, apoptosis mechanism, modern medicine on apoptosis detection methods, as well as Chinese herbal medicine-induced apoptosis of research are reviewed. One in modern medicine and Chinese medicine’s understanding of tumor cell apoptosis 1965, developmental biologist Lockshin and Willianms first proposed PCD (Programmed Cell Death, programmed cell death) the term used to describe the physiological cell death moth larvae. 1972, Kerr and other point of view from the morphological description of the physiological cell death, and this cell death, called apoptosis (apoptosis) [1]. Apoptosis also known as programmed cell death (PCD). Terminology for the morphology of apoptosis, programmed cell death as a functional terms [2], the current literature, many prefer the term apoptosis that such death was caused by external factors that trigger the cell death mechanism of the inner and eventually led to the cells their own death. External factors may be physical in nature, also may be non-physical in nature, the occurrence of apoptosis in the organization is not synchronized. In vivo, apoptotic body formation was once close to the epithelial cells, macrophages engulf cells or tumor cells and be degraded within lysosomes. This process is not the release of cell contents, does not cause inflammation, with necrosis obvious