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Citalopram in the treatment of somatoform disorders in clinical controlled study
[Abstract] Objective citalopram treatment of somatoform disorders in the clinical efficacy and safety. Methods 80 patients with somatoform disorders were randomly divided into two groups, were given citalopram and amitriptyline in a 6-week treatment study by Khan, Hamilton Depression Scale (HAMD, side effects scale (TESS 1,2,4,6 in the weekend before treatment efficacy and adverse effects were assessed. Results of citalopram and amitriptyline in the treatment of somatoform disorders similar efficacy, but citalopram than amitriptyline rapid onset of adverse reactions and light, and efficacy index is better than amitriptyline (P lt;0.05. Conclusion Citalopram treatment of somatoform disorders is effective, safe and rapid onset .
[Keywords:] Citalopram Amitriptyline somatoform disorders
Somatoform disorder is a lasting fear or believe that the advantages of a variety of somatic symptoms characterized by the concept of neurosis, the main feature is the repeated statement of physical discomfort of patients, repeated medical treatment, despite all the medical tests are normal, or even check the anomalies and do not conform to the current severity of symptoms, the doctors can not be explained repeatedly to dispel doubts, the patient was very painful and anxiety so. antidepressants as treatment of somatoform disorders drug of choice. citalopram for the treatment of somatoform disorders and the efficacy of Adverse reactions were compared to studies with amitriptyline, will now report the following observations.
1 Materials and Methods
1.1 General information on 80 cases of patients as our hospital from May 2006 to May 2008 hospitalized patients, the first application of antipsychotic drugs. All patients before the investigation into the group of blood, urine, liver function and electrocardiogram were normal, ruled out a serious heart, liver, kidney and
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