Clearing heat and dampness method of ulcerative colitis mucosal injury in rats.docVIP

Clearing heat and dampness method of ulcerative colitis mucosal injury in rats.doc

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 PAGE \* MERGEFORMAT 17 Clearing heat and dampness method of ulcerative colitis mucosal injury in rats Of: Zhang Haiyan, Huang Suiping, Huang Shaogang, Zhang Xiangfei, Wang Jing [Abstract] Objective To investigate the heat dampness Act (intestinal clear his enema enema + Changyanqing 1 feeding on experimental ulcerative colitis (UC) mucosal damage in rats, serum and colon tissue SOD activity and MDA content . Methods 51 adult female SD rats, 8 rats were randomly selected first as the normal group, not modeling, and the remaining 43 rats to the modeling, the first 3 days randomly selected from two dissected whether modeling successful, the remaining 41 rats were randomly divided into model group 11, intestinal clear his group, intestinal Di Qing Qing + enteritis group, sulfasalazine (SASP) group 10. made the 4th day after operation, normal group and model group were given saline enema, and the remaining three groups were given clear his bowel enema, intestine enema + Changyanqing clear his stomach, SASP enema + gavage for 2 weeks., respectively, the general situation from rat colon mucosal damage index and the pathological changes, serum and colon tissue SOD activity and MDA content in heat dampness method to observe the 2,4,6 - trinitrobenzene sulfonic acid-induced experimental UC in rats and its mechanism. Results model group and the other two treatment groups, intestinal Di Qing Qing + colitis UC can significantly improve the situation in rats, diarrhea and blood in the stool, reduce the colon mucosal damage index, improved the pathological situation of the colon mucosa, increased serum and colonic tissue SOD energy, reduce serum and colon tissue MDA content. Conclusion Gut SD Changyanqing polyester may be through increased serum and colonic tissue SOD activity and lower MDA content to achieve the experimental UC in rats. [Keywords:] clearing heat and dampness law colitis ulcerative colitis, 1 Qing Qing enema intestinal wash Abstract: ObjectiveTo

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