Combination of hepatitis B markers in liver damage and ALT in judging the replication status of HBVDNA Analysis of 789 cases of.docVIP

 PAGE \* MERGEFORMAT 4 Combination of hepatitis B markers in liver damage and ALT in judging the replication status of HBVDNA Analysis of 789 cases of Authors: Fan Hongyan, Zhang Feng, PENG Jun-hua, DENG Zhi-yun [Abstract] Objective To investigate 789 cases of hepatitis B virus surface antigen (HBsAg)-positive population in peripheral blood of liver injury and cases of hepatitis B virus replication. Methods statistically analyzed 789 cases of positive HBsAg, hepatitis B markers at the same time 5, ALT, and HBV  DNA test results distribution. The results of HBsAg-positive persons, ALT abnormal rate of 27.8%, while the HBV  DNA replication rate was 49.3%. Combination of hepatitis B markers between the abnormal rate of ALT and HBV  DNA replication rate is different. HBeAg-positive and ALT abnormalities, HBV  DNA replication rate was 93.1%. February 2009 37 No. 1 Clinical Medical Journal (Clin J Med Offic) concluded with the combination of hepatitis B markers of ALT may be a better understanding of liver injury and HBV  DNA replication, they can help to determine condition. [Keywords:] Hepatitis B virus; hepatitis B markers; ALT; HBV  DNA Abstract: Objective To investigate the status of liver damage and HBV  DNA replication occurrence in periphery blood of 789 HBsAg positive cases. Methods The outcomes of five HBV markers (HBVMs), alanine aminotransferase (ALT) and HBV  DNA from 789 HbsAg  positive cases were statistically analyzed together.Results ALT abnormality rate of HbsAg  positive group was 27.8%, and HBV  DNA replication occurrence rate was 49.3%. The rates of ALT abnormality and HBV  DNA replication occurrence were different between the HBVM groups. The HBV  DNA replication occurrence rate in HBeAg  positive and ALT  abnormality group was up to 93.1%. Conclusion The combination of HBVMs and ALT well reflects the status of liver damage and HBV  DNA replication, and it may be helpful to diagnose illness. Keywords:: HBV; H